Dna platination
WebQuality control next-generation sequencing libraries with the High Sensitivity DNA assay on the 2100 Bioanalyzer System. Obtain reliable sample quality data, such as quantitation and sizing of DNA smears from library … WebNov 12, 2024 · The authors demonstrated that the complexes exhibit strong DNA-binding affinity via intercalation with binding constants in the range 0.30 × 10 5 –6.25 × 10 5 L/mol. Intriguingly, ... It is evident from these presented examples that platination may be an ingenious strategy to augment the efficacy of antimalarial agents, ...
Dna platination
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Platinum(II) acetylacetonate (97%), oleylamine (80–90%), lithium triethylborohydride, N-Hydroxysuccinimide sodium salt (NHS), N-(3-Dimethylaminopropyl)-N’-ethylcarbodiimide hydrochloride (EDC), cysteamine (CA), tetrahydrofuran (THF), N,N-dimethylformamide (DMF), 2-(N … See more Transmission electron microscopy (TEM) analysis was performed on a transmission electron microscope (Hitachi HT7700, Japan). High-resolution transmission electron microscopy … See more Pt nanoclusters (PtNCs) of ~2.5 nm in diameter were synthesized via the thermal decomposition method. In a typical process, 0.4 g of Platinum(II) acetylacetonate and … See more The Pt ion release behaviour of NMPNs after the discharge of mPEG5K-AC-CA at different time points (0.5, 2, 4, 8 h) was analyzed by using ICP-MS. First, NMPNs were treated with PBS (pH 6.5) for 6 h. Then, PBS (pH 6.5) … See more One gram of mPEG5K-OH (Mw = 5000) was dissolved in 15 mL of Ar-purged tetrahydrofuran (THF) under ice-water bath. Then, 460 μL of TEA and 200 μL of acryloyl chloride were slowly injected into the mixture. The … See more
WebCisplatin targets DNA, and DNA platination levels induced in HaCaT skin cells by 1 were similar to those of cisplatin. However, cisplatin forms mainly intrastrand cis diguanine … WebAt similar rates of DNA platination (r b = 0.025), compounds 2 and 3 unwind supercoiled pUC8 DNA by (48 ± 2)°. Altogether, these data suggest (i) ... DNA Interaction and …
WebApr 5, 2011 · Side effects sidelined: We compared the effects of various leaving groups and amines on the efficiency, kinetics, and mode of DNA platination by trans-platinum … WebA survey of selected N-heterocycle ligands showed that platination of 4-N-dimethylaminopyridine (DMAP) in [Pt(dien)L]2 + (dien = diethylenetriamine) gave …
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Web@article{osti_6620249, title = {Kinetic investigation of the DNA platination reaction: evidence for a transient adduct between deoxyribonucleic acid and cis-platinum(II)}, … good arch support sneakersWebBiosensors based on DNA self-assembled monolayers (DNA-SAMs) combined with electrochemical transducers have shown great potential to serve an important role in simple, accurate and inexpensive genetic analysis relevant to many fields. Recently we have reported on observing a significant change in the viscoelasticity of such DNA layers … healthiest baking sheetsWebMar 31, 2009 · Conclusion: The protective effect of recombinant erythropoietin is not mediated by reducing the burden of DNA platination in the target cells, but it is likely to … goodard school jacksonville beach flWebSep 21, 2024 · Furthermore, repression of specific DNA repair genes was restricted to oxaliplatin. Transcriptional level observations were further analyzed on the functional … good arctic fox namesWebCDDP-induced DNA-platination was demonstrated in rat DRG neurons using a schedule of chronic CDDP administration which induced the onset of a sensory neuronopathy with … healthiest banana bread recipe everWebDesign of polyfunctional probes for the detection and capture of nucleic acids secondary structures, G-quadruplex DNA, and associated proteins. - Management of several long-term research projects ... Subsequently the capacity of the compounds to establish one or two anchorage points (one by platination, one by photoinduced crosslinking) ... healthiest bananaWebKinetics of small molecules with RNA and DNA using analytical techniques. Analysis of impact of platination on glycosidic bond stability of nucleic acid residues. Selective … good areas in las vegas to live