WebTEAD1 is a transcription factor involved in activation of muscle specific genes, such as the cardiac muscle troponin T gene, skeletal muscle actin, myosin heavy chains genes. Here, we reported that TEAD1 was expressed ubiquitously in different mouse tissues and was up-regulated in differentiation process of the mouse myoblast cell line C2C12. WebDec 10, 2024 · We found that Tead1 in combination with GMT administration increased the expression of the cardiomyocyte marker cTnT in mouse embryonic and adult rat cardiac fibroblasts by ≈3‐fold compared with GMT administration alone (P<0.0001), whereas 2 other Hippo pathway effectors YAP and TAZ did not increase cTnT expression above GMT …
A genome-wide CRISPR-Cas9 knockout screen identifies …
WebMar 13, 2024 · After normalization to the relative Tead1 and Tead2 input and precipitation levels, Yap1 was found to coprecipitated 2.13-fold and Taz 13-fold more efficiently with Tead2 than with Tead1 (Fig. S8c,d). Transcriptional enhancer factor TEF-1 also known as TEA domain family member 1 (TEAD1) and transcription factor 13 (TCF-13) is a protein that in humans is encoded by the TEAD1 gene. TEAD1 was the first member of the TEAD family of transcription factors to be identified. hsmw jobteaser
TEAD family transcription factors in development and disease
WebDec 8, 2024 · Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth. YAP/TEAD1 Complex Is a Default Repressor of Cardiac Toll-Like Receptor Genes. Tead transcription factors differentially regulate cortical development. Transformation of normal cells by aberrant activation of … WebIn developing skeletal muscle and myocardium, in mitotic neuroblasts both in the brain and spinal cord. At later stages of embryogenesis expressed in several developing … WebTEAD1. CELL LINE. Human cell lines. GENERAL INFORMATIONi. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Gene namei. Official gene symbol, which is typically a short form of the gene name, according to HGNC. hsm wire international inc